Table of Contents Author Guidelines Submit a Manuscript
Comparative and Functional Genomics
Volume 2008, Article ID 879023, 6 pages
http://dx.doi.org/10.1155/2008/879023
Research Article

Protein Coding Gene Nucleotide Substitution Pattern in the Apicomplexan Protozoa Cryptosporidium parvum and Cryptosporidium hominis

1Department of Computer Science, Tufts University, Medford, MA 02155, USA
2Department of Biomedical Sciences, Tufts Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA 01536, USA

Received 18 November 2007; Accepted 29 March 2008

Academic Editor: Neil Hall

Copyright © 2008 Guangtao Ge et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Supplemental Figure 1 describes the distribution of synonymous substitution ratios of genes calculated using the YN00 method. Substitution ratios show the number of synonymous substitutions over synonymous substitution sites. Supplemental Figure 2 illustrates the distribution of nonsynonymous substitution ratios of genes calculated as nonsynonymous substitutions over nonsynonymous substitution sites. Supplemental Table 1 shows a list of orthologous gene pairs showing signs of positive selection (dN/dS > 1; YN00 method). Values of dN/dS estimated from NG 86 and ML94 methods, as well as functional annotations, are also presented.

  1. Supplemental Figure 1
  2. Supplemental Figure 2
  3. Supplemental Table 1