Research Article

Anaplasma phagocytophilum and Anaplasma marginale Elicit Different Gene Expression Responses in Cultured Tick Cells

Figure 3

Effect of A. phagocytophilum and A. marginale infection on tick ISE6 cells gene expression. The mRNA levels were compared between A. phagocytophilum- (white bars) and A. marginale- (black bars) infected tick ISE6 cells by real-time RT-PCR. Bars represent the ratio between infected normalized Ct values and uninfected average normalized Ct values (+SD). The mRNA levels were normalized against tick 16S rRNA and compared between A. phagocytophilum- and A. marginale-infected tick cells by Student’s -test (* ). Positive and negative values denote upregulation and downregulation, respectively, with respect to uninfected controls.
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