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GenBank ID | Gene Name | Function | Control versus WT Y. pestis CO92 at 48 hours |
| | | Liver | Lung | Spleen |
| | | FC |
|
|
AV309418 | N-myc downstream regulated 1 (Ndrg) | Regulation of progression through cell cycle; inflammatory response; immune response | 23.1 | 17.5 | 14.6 |
|
BM234360 | Fibronectin 1 (Fn1) | Acute-phase response | 53 | 29.4 | 6.7 |
|
BC010337 | Keratin 7 (Krt7) | Cytokine and chemokine mediated signaling pathway | 2 | 7.3 | 6.5 |
|
AY061760 | Nuclear factor, interleukin 3, regulated (Nfil3) | Electron transport; fat cell differentiation | 7.5 | 3.7 | 6.1 |
|
AK013239 | Inhibitor of DNA binding 2 (Id2) | Electron transport; cell motility; chemotaxis; inflammatory response; immune response; cell surface receptor linked signal transduction; cell-cell signaling; muscle development; circulation; positive regulation of cell proliferation | 30.5 | 20 | 6 |
|
AK013765 | Endothelial cell growth factor 1 (platelet-derived) (Ecgf1) | Immune response | 22.4 | 4.6 | 5.5 |
|
BG064671 | A disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 4 (ADAMTS4) | Regulation of cell growth; neutrophil apoptosis; inflammatory cell apoptosis; cell motility; immune response; response to virus; antigen processing and presentation; neutrophil chemotaxis; unfolded protein response; negative regulation of myelination; defense response to bacterium; positive regulation of chemokine biosynthesis | 4.2 | 4.3 | 5.4 |
|
AK004893 | Inter alpha-trypsin inhibitor, heavy chain 4 (Itih4) | Chemotaxis; inflammatory response; immune response; signal transduction | 8.8 | 9.3 | 5.3 |
|
NM_031192 | Renin 1 structural (Ren1) | Regulation of cell growth; regulation of protein amino acid phosphorylation; antiapoptosis; JAK-STAT cascade; negative regulation of insulin receptor signaling pathway | 15 | 4 | 5.3 |
|
NM_008326 | Immunity-related GTPase family, M (Irgm) | Immune response | 6.1 | 7.9 | 5.1 |
|
AW546137 | Bone morphogenic protein receptor, type II (serine/threonine kinase) (Bmpr2) | Response to stress; stress-activated protein kinase signaling pathway | 2.8 | 2.2 | 5.6 |
|
AV328143 | ADP-ribosylation factor-like 4A (Arl4a) | Unknown | 23.7 | 10.4 | 4.3 |
|
NM_011722 | Dynactin 6 (Dctn6) | Immune response; cell surface receptor linked signal transduction | 3.7 | 5.2 | 4.2 |
|
BB667823 | Ring finger protein 125 (Rnf125) | Immune response; response to virus | 11.1 | 7.2 | 4.1 |
|
BB561053 | Zinc finger, MYND domain containing 11 (Zmynd11) | Acute-phase response | 3.6 | 11.9 | 4 |
|
AF004023 | Cd200 antigen (Cd200) | Chemotaxis; inflammatory response; immune response; signal transduction | 2.7 | 3.3 | 3.8 |
|
BC025819 | Cytochrome P450, family 2, subfamily c, polypeptide 44 (Cyp2c44) | Immune response; cell adhesion; antimicrobial humoral response | 2.5 | 2.3 | 3.8 |
|
AK006551 | Coenzyme Q10 homolog B (Coq10b) | Apoptosis; immune response | 20.9 | 11.6 | 3.7 |
|
NM_011016 | Orosomucoid 2 (Orm2) | Immune response | 7.4 | 2.9 | 3.5 |
|
AF022957 | Acidic (leucine-rich) nuclear phosphoprotein 32 family, member A (Anp32a) | Somitogenesis; response to biotic stimulus; anterior/posterior pattern formation | 3.3 | 2 | 3.1 |
|
NM_023462 | Retinol binding protein 7, cellular (Rbp7) | Immune response | 4 | 4.3 | 3 |
|
BB223018 | Schlafen 1 (Slfn1) | Electron transport; lactation; regulation of epithelial cell differentiation | 3.5 | 3.5 | 2.8 |
|
BG076338 | F-box protein 21 (Fbxo21) | Immune response | 11.1 | 4.2 | 2.7 |
|
NM_008458 | Serine (or cysteine) peptidase inhibitor, clade A, member 3C (Serpina3c) | Regulation of progression through cell cycle; fever; apoptosis; inflammatory response; immune response; cell proliferation; regulation of cell proliferation; antimicrobial humoral response; neutrophil chemotaxis; positive regulation of chemokine biosynthesis; positive regulation of IL-6 biosynthesis; leukocyte migration | 7.2 | 7.1 | 2.5 |
|
AF047725 | Cytochrome P450, family 2, subfamily c, polypeptide 38 (Cyp2c38) | Unknown | 2.5 | 2.6 | 2.5 |
|
BC018333 | Aldo-keto reductase family 1, member D1 (Akr1d1) | NAD biosynthesis; pyridine nucleotide biosynthesis | 4.1 | 2.4 | 2.5 |
|
BC021340 | Poly (ADP-ribose) polymerase family, member 14 (Parp14) | Immune response | 4 | 7.8 | 2.4 |
|
BB326709 | Doublecortin and CaM kinase-like 3 (Dcamkl3) | Protein folding | 2.4 | 8.1 | 2.4 |
|
AF030178 | Phosphatidylinositol glycan anchor biosynthesis, class Q (Pigq) | Cytokine and chemokine mediated signaling pathway | 3.8 | 5.4 | 2.3 |
|
NM_008262 | One cut domain, family member 1 (Onecut1) | Phagocytosis; apoptosis; inflammatory response; immune response; cell surface receptor linked signal transduction | 30.9 | 4.3 | 2.3 |
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