Molecular Diversity of the Antimicrobial Domain of Beta-Defensin 3 and Homologous Peptides
Figure 3
Phylogenetic tree of mammalian BDEF3 orthologous group. Maximum parsimony tree with bootstrap confidence levels based on protein sequences of mammals. Primate-, ungulate-, cow-, and rodent-BDEF3 clusters were identified. Protein charges are similar within sequences of each BDEF3 cluster (, and , , , resp.). These results demonstrate that mammalian BDEF3 undergoes niche specialization during protein evolution.
