Factors Affecting Splicing Strength of Yeast Genes

Table 6

Position weight matrix scores (PWMSs, as a proxy for splicing strength) is significantly smaller for splice sites from intron-containing genes (ICGs) whose transcripts failed to recruit U1 snRNPs (NRG for nonrecruiting group) than for those from ICGs whose transcripts bind well to U1 snRNPs (RG for recruiting group). The pattern is consistent for both 5′ ss and 3′ ss, based on two-sample 𝑡-tests assuming equal variances. Mann-Whitney tests yield the same conclusion.

	5′ ss		3′ ss
	NRG	RG	NRG	RG
PWMS mean	8.8138	11.1978	5.3129	7.1762
PWMS Var.	31.5069	4.8646	13.3017	8.2077
𝑁	44	231	49	252
𝑡	−4.6346		−3.9257
𝑃	0.0000		0.0001