Applications of Different Weighting Schemes to Improve Pathway-Based Analysis

Table 13

Canine pathways whose ranks are significantly changed under RWM in the random forests.

Pathway ID and name	Ranks		OOB (%)
	Uniform	RWM	Uniform	RWM
PID 24 Alanine and aspartate metabolism	319	13	0.34	0.07
PID 59 Glycerolipid metabolism	242	13	0.28	0.07
PID 204 Role of PI3K subunit p85 in regulation of actin organization and cell migration	281	13	0.31	0.07
PID 229 Induction of apoptosis through DR3 and DR4/5 death receptors	157	4	0.21	0.07
PID 269 Ghrelin: regulation of food intake and energy homeostasis	188	4	0.28	0.07