International Journal of Genomics / 2012 / Article / Fig 2

Review Article

A Systems Approach and Skeletal Myogenesis

Figure 2

Proposed myogenesis regulatory network by our systems approach in myoblasts; Id proteins are expressed and inhibit the myogenic bHLH factors. During myogenic differentiation, RP58 is promoted by MyoD and represses the Id transcription. Muscle specific genes are then activated by myogenic bHLH factors.