mRNA 3′ End Processing Factors: A Phylogenetic Comparison

Figure 10

Domain homology of SYMP, PAPOLA, PABPN1, and PABPC4. Schematics of proteins are shown approximately to scale. The domains were identified by the NCBI conserved domain database or known published domains. Symplekin has SYMP-N, SYMP-C, and CstF binding domains. PAPOLA contains many domains including N-terminal, catalytic central, nuclear localization signal (NLS), serine/threonine-rich, and C-terminal domains. The nuclear and cytoplasmic PABP proteins contain RRM domains. PABPC1 has a protein-protein interacting PABC domain.