mRNA 3′ End Processing Factors: A Phylogenetic Comparison

Figure 6

Domain homology of the CstF complex. Schematics of proteins are shown approximately to scale. The domains were identified by the NCBI conserved domain database or known published domains. CSTF1 contains dimerization and WD40 domains involved in protein-protein interactions. CSTF2 has five domains: RRM, hinge, proline/glycine rich, MEARA/G, and CTD. The RRM is involved in CSTF2 RNA binding. The hinge and CTD domains are involved in protein-protein interactions. CSTF3 has three protein interacting domains: HAT-N, HAT-C, and proline-rich domains.