Comparative Analysis of Context-Dependent Mutagenesis in Humans and Fruit Flies
Figure 3
The difference between H. sapiens and D. melanogaster mutation bias ((a) and (b)) and minimal contrast ((c) and (d)) for 2–4 bp mutation contexts. Each dot represents a mutation context. The axis represents the contexts minimal contrast values, and the axis represents the contexts mutation bias. The minimal contrast and mutation bias values are given for H. sapiens ((a) and (c)) and for D. melanogaster ((b) and (d)), and the color scheme indicates the difference between minimal contrasts. Thus, red dots on (a) and (c) represent contexts that are hypermutable in humans comparing to drosophila, while green dots represent contexts that are hypermutable in D. melanogaster comparing to H. sapiens. This scheme is reversed for (b) and (d).
