Table 6: Interaction analyses of the TSP-1-1223 A/G polymorphism and tobacco smoking.

Smoking statusGenotypesCasesControls Crude OR (95% CI)a Adjusted OR (95% CI)b
% %

NonsmokersAA + AG27845.737756.31.00 (reference)1.00 (reference)
NonsmokersGG 39 6.4 49 7.3 0.7381.08 (0.67–1.73)0.3811.25 (0.76–2.05)
SmokersAA + AG25441.721532.1<0.0011.60 (1.25–2.05)0.0011.58 (1.20–2.10)
SmokersGG 38 6.2 29 4.3 0.0251.78 (1.04–3.06)0.1581.52 (0.85–2.73)
(multiplicative)0.823

CI: confidence interval; OR: odds ratio.
aTwo-sided test for either genotype distributions or allele frequencies between the cases and controls.
bAdjusted for age, gender, smoking, drinking status, and family history of cancer in logistic regression model.