Extensive Differences in Antifungal Immune Response in Two Drosophila Species Revealed by Comparative Transcriptome Analysis
Table 2
Number of reads, trimmed mean of M value (TMM), and induction coefficient (IC) for recognition, signaling, and effector class immune genes showing significant changes in expression level by fungal infection in D. virilis.
D. virilis gene
D. melanogaster homologue
Infected
Naïve
IC
Functional class
Notes
No. of reads
TMM
No. of reads
TMM
GJ20666
CG13422
6
0.153
0
0
Infinity
Recognition
Beta-glucan binding domain
GJ12160
PGRP-SB1
11
0.235
2
0.040
5.864
Recognition
PGRP domain
GJ18074
nimB3
2
0.067
12
0.376
0.178
Recognition
Nimrod-related
GJ12373
msn
9
0.024
1
0.002
9.595
Signaling
Kinase
GJ20603
Pvr
15
0.038
2
0.005
7.996
Signaling
Receptor
GJ19441
SPE
3
0.033
15
0.155
0.213
Signaling
Protease
GJ22479
Def
53
2.445
0
0
Infinity
Effector
Antimicrobial peptide
GJ21173
AttC
47
0.818
0
0
Infinity
Effector
Antimicrobial peptide
Cec2B
CecA1/CecA2
25
1.604
0
0
Infinity
Effector
Antimicrobial peptide
Cec3
CecC
23
1.475
0
0
Infinity
Effector
Antimicrobial peptide
GJ22469
Mtk
9
0.660
0
0
Infinity
Effector
Antimicrobial peptide
GJ19916
Dpt
104
3.812
4
0.138
27.720
Effector
Antimicrobial peptide
GJ19917
DptB
39
1.120
3
0.081
13.860
Effector
Antimicrobial peptide
GJ20572
AttA
49
0.856
24
0.393
2.177
Effector
Antimicrobial peptide
GJ17981
fon
217
1.641
370
2.624
0.625
Effector
Coagulation
GJ18607
IM4
79
7.542
151
13.521
0.558
Effector
IM
GJ21308
IM10
23
0.350
51
0.727
0.481
Effector
IM
GJ19885
IM1
37
3.302
123
10.296
0.321
Effector
IM
Genes are sorted in order of induction coefficient at each functional class.