Extensive Differences in Antifungal Immune Response in Two Drosophila Species Revealed by Comparative Transcriptome Analysis
Table 3
Number of reads, trimmed mean of M value (TMM), and induction coefficient (IC) for recognition, signaling, and effector class immune genes showing significant changes in expression level by fungal infection in D. melanogaster.
D. melanogaster gene
Infected
Naïve
IC
Functional class
Notes
No. of reads
TMM
No. of reads
TMM
PGRP-SB1
29
0.779
0
0
Infinity
Recognition
PGRP domain
PGRP-SC1b
11
0.288
0
0
Infinity
Recognition
Amidase degradation
PGRP-SB2
9
0.225
0
0
Infinity
Recognition
PGRP domain
Mcr
4
0.011
0
0
Infinity
Recognition
Tep
PGRP-SC2
20
0.603
3
0.102
5.891
Recognition
Amidase degradation
TepII
188
0.708
31
0.132
5.359
Recognition
Tep
nimC2
43
0.310
9
0.073
4.222
Recognition
Nimrod-related
GNBP3
15
0.164
4
0.049
3.313
Recognition
Beta-glucan binding domain
CG13422
17
0.569
5
0.189
3.004
Recognition
Beta-glucan binding domain
TepIV
37
0.131
13
0.052
2.515
Recognition
Tep
PGRP-SD
27
0.626
13
0.341
1.835
Recognition
PGRP domain
Rel
14
0.067
0
0
Infinity
Signaling
Transcription factor
aop
6
0.026
0
0
Infinity
Signaling
Transcription factor
brm
5
0.016
0
0
Infinity
Signaling
Transcription factor
Myd88
4
0.019
0
0
Infinity
Signaling
—
CG6361
15
0.185
1
0.014
13.254
Signaling
Protease
cact
11
0.081
1
0.008
9.720
Signaling
—
dom
8
0.085
1
0.012
7.069
Signaling
Transcription factor
Stat92E
11
0.050
3
0.016
3.240
Signaling
Transcription factor
srp
18
0.080
5
0.025
3.181
Signaling
Transcription factor
phl
32
0.135
9
0.043
3.142
Signaling
—
mask
10
0.012
3
0.004
2.945
Signaling
—
spirit
22
0.231
7
0.083
2.777
Signaling
Protease
CecC
35
1.521
0
0
Infinity
Effector
Antimicrobial peptide
CecA1
14
0.663
0
0
Infinity
Effector
Antimicrobial peptide
Def
11
0.461
0
0
Infinity
Effector
Antimicrobial peptide
CecB
7
0.288
0
0
Infinity
Effector
Antimicrobial peptide
dro5
6
0.276
0
0
Infinity
Effector
Antimicrobial peptide
AttC
252
4.684
2
0.042
111.333
Effector
Antimicrobial peptide
Dpt
343
11.568
24
0.916
12.628
Effector
Antimicrobial peptide
DptB
80
2.974
6
0.252
11.781
Effector
Antimicrobial peptide
Pu
79
0.687
7
0.069
9.972
Effector
Melanin synthesis cascade
TotC
10
0.311
1
0.035
8.836
Effector
Tot
IM18
62
1.403
8
0.205
6.848
Effector
IM
Mtk
380
23.719
52
3.673
6.457
Effector
Antimicrobial peptide
Dro
192
4.237
27
0.674
6.283
Effector
Antimicrobial peptide
yellow-f
23
0.277
6
0.082
3.387
Effector
Melanin synthesis cascade
IM14
68
5.101
19
1.613
3.162
Effector
IM
AttA
96
2.113
27
0.673
3.142
Effector
Antimicrobial peptide
IM4
56
2.194
16
0.709
3.093
Effector
IM
IM10
355
6.147
116
2.273
2.704
Effector
IM
IM1
247
11.541
82
4.336
2.662
Effector
IM
AttB
74
1.428
27
0.590
2.422
Effector
Antimicrobial peptide
IM2
139
6.250
62
3.155
1.981
Effector
IM
Tsf1
145
1.209
68
0.642
1.884
Effector
Iron binding
TotA
182
5.213
98
3.177
1.641
Effector
Tot
Drs
551
23.817
299
14.627
1.628
Effector
Antimicrobial peptide
Tig
22
0.053
12
0.033
1.620
Effector
Coagulation
IM3
330
18.401
188
11.864
1.551
Effector
IM
Genes are sorted in order of induction coefficient at each functional class.
