International Journal of Genomics / 2014 / Article / Tab 1

Research Article

Associations of CTLA4 Gene Polymorphisms with Graves’ Ophthalmopathy: A Meta-Analysis

Table 1

General characteristics of the selected studies in the meta-analysis.

EthnicCountrySNP genotypingGrouping methodEligible subjectsFirst author (year) [reference]
GONon-GOGONon-GO

EuropeanUSARFLP NOSPEC3–6No clinical feature8552 Villanueva (2000) [16]
UKRFLPNOSPEC3–6NOSPEC < 3161323Allahabadia (2001) [17]
SloveniaRFLPClinical featuresNo clinical feature3334Zaletel (2002) [18]
IranRFLPNOSPEC3–6NOSPEC < 3105100Esteghamati (2009) [24]
PolandRFLPNOSPEC3–6No clinical feature95169Bednarczuk (2003) [19]
UKRFLPNOSPEC3–6NOSPEC < 3124168Vaidya (2003) [11]
PolandMinisequencingNOSPEC3–6NOSPEC < 35049Frydecka (2004) [13]
ItalyRFLPNOSPEC2–6NOSPEC < 39060Petrone (2005) [20]

AsianChinaDCFHNOSPEC3–6NOSPEC < 3142119Han (2006) [21]
ChinaRFLPNOSPEC3–6No clinical feature3356Zhang (2006) [22]
ChinaRFLPNOSPEC2NOSPEC3, 43422Chong (2008) [23]
JapanRFLPNOSPEC3–6No clinical feature99220Bednarczuk (2003) [19]
KoreaRFLPClinical featureNo clinical feature2647Park (2000) [15]