Comparison of Metabolic Network between Muscle and Intramuscular Adipose Tissues in Hanwoo Beef Cattle Using a Systems Biology Approach

Table 1

List of oppositely up- or downregulated KEGG pathways in the longissimus dorsi intramuscular adipose tissue compared to muscle and subcutaneous adipose and omental adipose tissues in Hanwoo.

	KEGG ID	Pathway	Fold enrichment	Bonferroni
Upregulated	bta04510	Focal adhesion^†	2.7
	bta04512	ECM-receptor interaction^†	3.7
	bta04360	Axon guidance^†	2.8
	bta05200	Pathways in cancer	1.8
	bta04270	Vascular smooth muscle contraction	2.4
	bta04062	Chemokine signaling pathway^†	2.0
	bta05412	Arrhythmogenic right ventricular cardiomyopathy	2.8
	bta04810	Regulation of actin cytoskeleton^†	1.9
	bta05414	Dilated cardiomyopathy	2.5
Downregulated	bta00190	Oxidative phosphorylation^‡	6.2
	bta05012	Parkinson’s disease^‡	6.0
	bta05016	Huntington’s disease^‡	4.8
	bta05010	Alzheimer’s disease^‡	4.8
	bta00020	Citrate cycle (TCA cycle)^‡	10.5
	bta03050	Proteasome^‡	7.0
	bta00280	Valine, leucine, and isoleucine degradation	5.9
	bta00640	Propanoate metabolism	6.7
	bta00071	Fatty acid degradation	5.4
	bta00650	Butanoate metabolism	5.4
	bta00620	Pyruvate metabolism^‡	4.7

Downregulated in the muscle tissue.
Upregulated in the muscle tissue.