OPN Polymorphism Is Related to the Chemotherapy Response and Prognosis in Advanced NSCLC

Table 1

Patient characteristics between well responder and poor responders to platinum-based chemotherapy.

Characteristics patient	Well responder		Poor responder		𝑃
Age (years)	52.8 ± 3.2	%	53.0 ± 5.1	%	0.083
Gender
Male	100	59.88%	198	60.00%	0.281
Female	67	40.12%	132	40.00%
Smoke status
nonsmokers	110	65.87%	163	49.39%	0.025
smoker	57	34.13%	167	50.61%
Histology
Squamous cell carcinoma	80	47.90%	166	50.30%	0.225
Adenocarcinoma	87	52.10%	164	49.70%
Stage
IIIB	101	60.48%	165	50.00%
IV	66	39.52%	165	50.00%
Differentiation
Well	68	40.72%	87	26.36%	0.016
Moderate	54	32.34%	135	40.91%
Poor	45	26.95%	108	32.73%
Chemotherapy regimens
DDP/CBP + TAX/TXT/DOC	87	52.10%	110	33.33%	0.15
DDP/CBP + GEM	65	38.92%	122	36.97%
DDP/CBP + NVB	15	8.98%	98	29.70%