Genetic Vectors as a Tool in Association Studies: Definitions and Application for Study of Rheumatoid Arthritis

Figure 1

The example of the OR-distribution at fixed the density of probability for hypergeometric distribution versus odds ratio . As seen, the distribution is asymmetric. The plot is built for the following parameters: ; ; . The expectation value (shown by green line), the threshold OR, . This is the solution to (18), meaning that the sum of probabilities from till (shown by red vertical lines) is equal to . At the end, the probability of finding OR greater than the experimental value of the odds ratio, , equals 0.04; the value is taken from experiments, described above, and is shown by a black star ().