RECORD: Reference-Assisted Genome Assembly for Closely Related Genomes

Figure 4

Comparison of the proposed approach (RECORD) with two state-of-the-art genome assemblers on data simulated with wgsim. In this experiment, we consider the evolved genome produced by Evolver as the target genome; the reference genome is the ancestral genome. The diagrams show the performance of the examined approaches according to various criteria as the function of the number of simulated reads that were used for the assembly. The diagram (a) shows the number of covered bases of the target genome; the diagram (b) shows the accuracy, that is, overall percentile identity between the assembly contigs and the corresponding segments of the target genome, while the diagram (c) shows the number of those largest contigs that together cover at least 50% of the target genome.

(a)

(b)

(c)