Revealing Genomic Profile That Underlies Tropism of Myeloma Cells Using Whole Exome Sequencing

Table 1

Gene list of two cell lines.

Gene symbol	Chromosome	Protein change	Functional effect	Variant type	Frequency in cBioportal
SNU_MM1393_BM
NEK2	1	N→S	Benign	Nonsynonymous_SNV	0%
IARS2	1	None	None	Nonsynonymous_SNV	0%
OR2T33	1	P→L	Possibly_damaging	Nonsynonymous_SNV	0%
PPIG	2	D→E	Benign	Nonsynonymous_SNV	1%
AOX1	2	None	None	Nonsynonymous_SNV	1%
TMEM129	4	None	None	Nonsynonymous_SNV	0%
UNC5CL	6	R→G	Benign	Nonsynonymous_SNV	0%
ARHGEF10	8	None	None	Nonsynonymous_SNV	2%
H1FNT	12	R→Q	Benign	Nonsynonymous_SNV	1%
ZIC2	13	None	None	Nonsynonymous_SNV	0%
TMX1	14	None	None	Nonsynonymous_SNV	0%
PANK2	20	G→A	Benign	Nonsynonymous_SNV	0%
SNU_MM1393_SC
RBM15	1	None	None	Nonsynonymous_SNV	0.50%
OPTC	1	L→P	Benign	Nonsynonymous_SNV	0%
OR5H1	3	T→I	Possibly_damaging	Nonsynonymous_SNV	0%
MRPL23	11	D→N	Benign	Nonsynonymous_SNV	0%
FRY	13	None	None	Nonsynonymous_SNV	1%
KIAA1199	15	None	None	Nonsynonymous_SNV	0%
AP3B2	15	None	None	Nonsynonymous_SNV	1%
IL27	16	L→P	Probably_damaging	Nonsynonymous_SNV	0%
KIF1C	17	None	None	Nonsynonymous_SNV	1%
ZNF486	19	None	None	Nonsynonymous_SNV	0%
ARSE	X	None	None	Nonsynonymous_SNV	1%

cBioportal data of multiple myeloma.