Research Article
Transcriptome Analysis of Bovine Ovarian Follicles at Predeviation and Onset of Deviation Stages of a Follicular Wave
Table 3
List of upregulated genes in ODF1 versus PDF1 and their functions.
| | Gene symbol | GenBank number | PDF1 RPKM | ODF1 RPKM | Fold change | FDR corrected value | Gene product functions |
| | GAPDH | XM_001252511.3 | 1.91 | 59.65 | 31.91 | 9.83 × 10−11 | Microtubule and NAD binding | | BOLA-N | NM_001105651.1 | 14.28 | 174.88 | 12.50 | | Unknown | | PPP1R14A | NM_001193070.1 | 6.06 | 65.75 | 11.08 | 8.98 × 10−10 | Smooth muscle contraction | | LOC505676 | NM_001193296.1 | 14.04 | 111.19 | 8.09 | | Unknown | | LOC100337308 | XM_002684003.1 | 3.72 | 23.27 | 6.39 | 4.40 × 10−2 | Unknown | | MT1A | NM_001040492.2 | 26.50 | 150.75 | 5.81 | | Bind heavy metals | | LOC100125916 | NM_001105487.1 | 14.80 | 83.88 | 5.78 | 1.51 × 10−9 | Unknown | | TNFAIP6 | NM_001007813.1 | 11.17 | 46.61 | 4.26 | 1.06 × 10−3 | Cell-cell and cell-matrix interactions | | BEX2 | NM_001077034.1 | 93.97 | 345.00 | 3.75 | | Mitochondrial apoptosis | | GPR85 | NM_001075150.2 | 10.06 | 35.54 | 3.61 | 4.05 × 10−2 | G-protein coupled receptor | | PPM1K | NM_001046474.1 | 34.75 | 108.32 | 3.18 | 2.52 × 10−7 | Cellular survival and development | | CYP19A1 | NM_174305.1 | 656.88 | 1944.89 | 3.02 | | Estrogen biosynthesis | | MT1E | NM_001114857.1 | 54.11 | 152.16 | 2.87 | 2.61 × 10−9 | Bind heavy metals | | ETNK2 | XM_002693881.1 | 22.35 | 61.96 | 2.83 | 4.65 × 10−3 | Ethanolamine phosphorylation | | CHST11 | NM_001192668.1 | 57.39 | 154.72 | 2.75 | 6.77 × 10−9 | Biosynthesis chondroitin sulfate | | MT2A | NM_001075140.1 | 49.37 | 130.49 | 2.70 | 4.16 × 10−7 | Bind heavy metals | | PRSS23 | NM_001080306.1 | 58.01 | 151.79 | 2.67 | 2.74 × 10−8 | Follicular atresia | | TXNIP | NM_001101875.2 | 98.64 | 231.47 | 2.40 | 6.64 × 10−11 | Oxidative stress mediator | | NPR3 | NM_174127.2 | 47.55 | 106.35 | 2.28 | 5.93 × 10−4 | Natriuretic peptide hormone receptor | | GREB1 | NM_001205631.1 | 35.17 | 78.20 | 2.27 | 1.30 × 10−2 | Estrogen-stimulated cell proliferation | | EIF4EBP1 | NM_001077893.1 | 138.11 | 294.07 | 2.17 | 1.30 × 10−11 | Mediates protein translation regulation | | PIK3R1 | NM_174575.1 | 113.42 | 210.95 | 1.90 | 1.21 × 10−5 | Insulin actions metabolic | | LRP8 | NM_001097565.1 | 1061.54 | 1897.64 | 1.82 | | Sperm maturation | | SCD5 | NM_001076945.1 | 124.08 | 210.97 | 1.74 | 4.25 × 10−4 | Energy metabolism | | ENO1 | NM_174049.2 | 1005.45 | 1707.61 | 1.73 | | Tumor suppressor | | LDHA | NM_174099.2 | 221.85 | 366.73 | 1.69 | 3.41 × 10−7 | Affiliated with lncrna | | SERPINE2 | NM_174669.2 | 6816.85 | 11075.44 | 1.66 | | Serine protease inhibitor | | INHBA | NM_174363.2 | 5824.46 | 9440.24 | 1.65 | | Regulate gonadal stromal cell proliferation | | TMEM176B | NM_001099145.1 | 106.45 | 170.39 | 1.63 | 2.16 × 10−2 | Dendritic cells maturation | | OAT | NM_001034240.1 | 395.42 | 630.73 | 1.63 | 1.71 × 10−11 | Ornithine aminotransferase | | CYP11A1 | NM_176644.2 | 908.97 | 1425.87 | 1.60 | | Cholesterol to pregnenolone | | OBSL1 | XM_002685586.1 | 221.33 | 338.40 | 1.56 | 1.16 × 10−4 | Regulate ubiquitin ligase complex | | ARFGAP3 | NM_001075974.1 | 273.92 | 418.22 | 1.56 | 5.26 × 10−6 | Gtpase-activating protein | | ITGB5 | NM_174679.2 | 153.24 | 233.56 | 1.56 | 7.68 × 10−3 | Fibronectin receptor | | INHA | NM_174094.3 | 6341.61 | 9658.83 | 1.55 | | Gonadal hormone secretion | | OPTN | NM_001034602.1 | 160.13 | 243.40 | 1.55 | 5.92 × 10−3 | Affect cell death | | PTGR1 | NM_001035281.1 | 200.07 | 301.66 | 1.54 | 9.40 × 10−4 | Inactivation of the chemotactic factor | | STBD1 | XM_002688357.1 | 143.24 | 215.66 | 1.54 | 2.15 × 10−2 | Bind to carbohydrates | | LOC532189 | XR_083049.1 | 340.18 | 510.18 | 1.53 | 5.69 × 10−7 | Carboxypeptidase | | TMEM20 | NM_001076470.1 | 191.10 | 286.48 | 1.53 | 2.10 × 10−3 | Solute carrier | | ECE1 | NM_181009.2 | 461.24 | 691.33 | 1.53 | 8.98 × 10−10 | Converts big endothelin-1 to endothelin-1 | | GNG10 | NM_001114512.1 | 617.73 | 918.26 | 1.52 | 7.59 × 10−13 | Signal transducer |
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