International Journal of Genomics / 2016 / Article / Tab 5

Research Article

Transcriptome Analysis of Bovine Ovarian Follicles at Predeviation and Onset of Deviation Stages of a Follicular Wave

Table 5

Differentially expressed genes between ODF1 and PDF1 with known or predicted roles in follicular development.

Gene symbolFold changeFDR corrected valueUp- or downregulation in ODF1/PDF1Gene product functions

PPM1K3.182.52 × 10−7UpregulationCellular survival and development
BEX23.75UpregulationMitochondrial apoptosis
CYP19A13.02UpregulationEstrogen biosynthesis
PRSS232.672.74 × 10−8UpregulationFollicular atresia
GREB12.271.30 × 10−2UpregulationEstrogen-stimulated cell proliferation
SERPINE21.66UpregulationSerine protease inhibitor
INHBA1.65UpregulationRegulate gonadal stromal cell proliferation
CYP11A11.60UpregulationCholesterol to pregnenolone
INHA1.55UpregulationGonadal hormone secretion
TNFAIP64.261.06 × 10−3UpregulationCell-cell and cell-matrix interactions
OPTN1.555.92 × 10−3UpregulationAffect cell death
PRSS35−2.381.21 × 10−5DownregulationOvulation and CL formation and regression
APOA1−1.871.07 × 10−2DownregulationActivates spermatozoa motility
GSTA5−1.694.93 × 10−2DownregulationGlutathione transferase

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