Analysis of Gene Expression in an Inbred Line of Soft-Shell Clams (Mya arenaria) Displaying Growth Heterosis: Regulation of Structural Genes and the NOD2 Pathway

Figure 3

Significantly differentially regulated genes in NOD2 Pathway. Genes significantly upregulated in the RNAseq screen (heavily outlined boxes). Post hoc analysis found notable differences in expression level in RIPK2 nine isoforms (five with average 3.3-fold increase, average value 0.053, three isoforms ns, and one with 1.5-fold change), ERK/MAPK14 isoforms (one with 3.8-fold increase, , three ns), JNK/MAPK8 three isoforms (fold difference 4.1, , two other isoforms ns), and NFκB (fold difference 4.08, ). The following showed no significant difference in expression level: ERBIN, iKKB, CASP8, TAK1, TRAF6, TRIP6, SGT1, and CARD6.