Drug Target Identification and Prioritization for Treatment of Ovine Foot Rot: An In Silico Approach

Table 3

List of 13 proteins in Dichelobacter nodosus that were common in at least 10 pathogenic bacterial species. The results for the choke-point analysis for each protein are also tabulated.

S. number	Protein	KEGG ID	Choke-point protein (yes/no)
1	Cell division protein FtsI	K03587	Yes
2	UDP-muramoylpentapeptide beta-N-acetylglucosaminyltransferase (MurG)	K02563	Yes
3	30S ribosomal protein S3	K02982	No
4	UDP-N-acetylglucosamine 1-carboxyvinyltransferase (MurA)	K00790	Yes
5	Cell division protein FtsZ	K03531	No
6	D-Alanine-D-alanine ligase	K01921	No
7	RNA polymerase sigma-32 factor	K03089	No
8	UDP-N-acetylmuramate-alanine ligase (MurC)	K01924	Yes
9	Replicative DNA helicase	K02314	No
10	RNA polymerase sigma-70 factor	K03086	No
11	Transcription termination factor	K02600	No
12	Penicillin-binding protein 2	K05515	Yes
13	DNA polymerase III subunit alpha	K02337	No

indicates proteins that are among the 29 proteins listed in Table 2.