miRNA Expression Profile and Effect of Wenxin Granule in Rats with Ligation-Induced Myocardial Infarction

Figure 4

KEGG annotations of differentially expressed miRNAs from left ventricular tissue samples of MI rats (model group) and non-MI rats (control group). The miRNA versus pathway heatmap was created directly from the DIANA-miRPath v3.0 online tool. The heatmap depicts the level of enrichment in pathways of 35 differentially expressed miRNAs between MI and non-MI rats identified by microarray. There were 23 predicted pathways integrating with 35 differentially expressed miRNAs in the heatmap. The pathway clustering tree is shown on the top, and the legend on the bottom indicates the pathway represented in the corresponding column. The miRNA clustering tree is shown on the left, and the legend on the right indicates the miRNA represented in the corresponding row. The color scale shown on the upper left corner illustrates the predicted correlation degree of pathways with the miRNAs (shown as log value).