Research Article

MicroRNA Profiling in Cartilage Ageing

Figure 2

Cartilage expression profiling using an MA plot. The MA plot contrasts the log2 fold change (log2FC) against the mean intensity of all 12 arrays. The coloured spots represent DE small RNAs (FDR < 0.05), green dots reduced expression in the old OA samples, and red dots increased expression in the old OA samples. 20 miRs were significantly dysregulated; one increased in OA and 19 decreased in OA.