Research Article

Evidence of Divergent Amino Acid Usage in Comparative Analyses of R5- and X4-Associated HIV-1 Vpr Sequences

Table 3

HIV-1 Vpr positions with high Jensen-Shannon divergence between R5- and X4-associated sequences. The calculated Jensen-Shannon divergence, along with the associated value in parentheses (in italics when ), is displayed for positions 36, 37, 41, 89, and 96.

PositionAll residuesMurphy-15Murphy-10Murphy-8Murphy-4

360.03460.03410.03410.03410.0331
(0.0367)(0.0205)(0.0143)(0.0271)(0.0068)
370.16120.09500.07150.07090.0656
(0.0053)(0.0322)(0.0555)(0.0389)(0.0026)
410.10120.10120.07350.07350.0072
(0.0013)(0.0005)(0.0024)(0.0034)(0.4613)
890.10940.10940.10480.10340.0704
(0.0103)(0.0029)(0.0027)(0.0013)(0.0034)
960.06230.06230.06230.06230.0000
(0.0051)(0.0029)(0.0030)(0.0030)(0.5005)