Vitamin D Receptor Gene Polymorphisms Influence T1D Susceptibility among Pakistanis

Table 3

Haplotype analysis of the VDR gene located on chromosome 12.

Haplotype (rs731236-rs2228570-rs7975232-KT280406)	Case (freq)	Control (freq)	value
CTGG	0.046	0.860	0.001^۞
CTTG	0.054	0.014	0.004^۞
CCGC	0.035	0.000	0.007
CCGG	0.368	0.000	0.002
CCTC	0.051	0.000	0.001
CCTG	0.434	0.000	0.006

represents a significant association of haplotypes with T1D. ^۞ represents a significant association of haplotypes protective against T1D.