International Journal of Genomics

Review Article

Molecular Crosstalking among Noncoding RNAs: A New Network Layer of Genome Regulation in Cancer

Table 1

miRNAs inducing degradation of lncRNAs.


miRNA	lncRNA/circRNA target	Tumor	miRNA role	PMID

let-7b	lincRNA-p21	Cervical carcinoma	Tumor suppressor	22841487
let-7b, let-7i	HOTAIR	Cervical carcinoma	Tumor suppressor	24326307
miR-1	UCA1	Bladder cancer	Tumor suppressor	25015192
miR-9	MALAT1	Hodgkin lymphoma, glioblastoma	Tumor suppressor	23985560
miR-21	CASC2	Renal cell carcinoma	Oncogene	27222255
miR-21	CASC2	Glioblastoma	Oncogene	25446261
miR-21	GAS5	Breast cancer	Oncogene	23933812
miR-34a	HOTAIR	Prostate cancer	Tumor suppressor	23936419
miR-101	MALAT1	Esophageal squamous cell carcinoma	Tumor suppressor	25538231
miR-125b	HOTTIP	Hepatocellular carcinoma	Tumor suppressor	25424744
miR-125b	MALAT1	Bladder cancer	Tumor suppressor	24396870
miR-141	H19	Gastric cancer	Tumor suppressor	26160158
miR-141	HOTAIR	Renal carcinoma	Tumor suppressor	24616104
miR-217	MALAT1	Esophageal squamous cell carcinoma	Tumor suppressor	25538231
miR-671	CDR1AS	Glioblastoma	Oncogene	26683098

This table reports for each miRNA: (1) its lncRNAs/circRNA target; (2) tumor where such interaction was reported; (3) its function in cancer (oncogene or tumor suppressor); and (4) bibliographic reference reported as Pubmed ID (PMID).