Molecular Crosstalking among Noncoding RNAs: A New Network Layer of Genome Regulation in Cancer

Table 3

circRNAs acting as miRNA sponges.

circRNA	miRNA target	tumor	circRNA role	PMID
circRNA_0005075	miR-23b-5p, miR-93-3p, miR-581, miR-23a-5p	Hepatocellular carcinoma	Oncogene	27258521
circRNA_001569	miR-145	Colorectal cancer	Oncogene	27058418
circRNA_100290	miR-29 family	Oral cancer	Oncogene	28368401
Cdr1as	miR-7	Hepatocellular carcinoma	Oncogene	27391479
cir-ITCH	miR-7, miR-20a	Colorectal cancer	Tumor suppressor	26110611
cir-ITCH	miR-7, miR-17, miR-214	Esophageal squamous cell carcinoma	Tumor suppressor	25749389
ciR-SRY	miR-138	Cholangiocarcinoma	Oncogene	27671698, 23446431
cir-TTBK2	miR-217	Glioma	Oncogene	28219405

This table reports for each circRNA: (1) miRNAs sponged; (2) tumor where such interaction was reported; (3) its function in cancer (oncogene or tumor suppressor); and (4) bibliographic reference reported as Pubmed ID (PMID).