Chimeric Genes in Deletions and Duplications Associated with Intellectual Disability

Figure 4

(a) Sequences from both ends of the ZNF451-KIAA1586 chimera. (b) Digestion pattern of PCR amplicons of ZNF451, KIAA1586 and the chimera with RsaI and PstI. The size of each fragment is showed in brackets, the yellow box represents the segmental duplication, and PCR’s primers are indicated as black arrows. (c) Schematic representation of chimeric gene according to these results.

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