HuoXueJieDu Formula Alleviates Diabetic Retinopathy in Rats by Inhibiting SOCS3-STAT3 and TIMP1-A2M Pathways

Figure 4

HXJD reduces the expression of JAK2, p38 MAPK, and NF-κB in the retinas of diabetic rats. Distribution and expression of JAK2, p38 MAPK, and NF-κB were measured using IHC. (a–c) IHC staining of JAK2. (d–f) IHC staining of p38 MAPK. (g–i) IHC staining of NF-κB. Magnification: ×400. (j–l) Image analysis of JAK2, p38 MAPK, and NF-κB. A reduction of JAK2, p38 MAPK, and NF-κB was observed in the HXJD group. Data are represented as the means ± SEM. (). and , compared with the diabetic group.