Research Article
A Pilot Genome-Wide Association Study in Postmenopausal Mexican-Mestizo Women Implicates the RMND1/CCDC170 Locus Is Associated with Bone Mineral Density
Figure 1
Evidence of association of BMD in the femoral neck with the SLIT3 and CCDC170 chromosomal regions. The x-axis is the physical position on the chromosome (Mb), and the y-axis denotes the association test result as the −log ( value). SNPs are color-coded according to the linkage disequilibrium (LD) with the lead SNP (purple diamond) indicated by the arrow. (a) The SNP rs2278391 in the SLIT3 region; (b) the SNP rs17081341 in the RMND1/CCDC170 region. The regional association plots in the Morelos cohort were generated using LocusZoom and only show genotyped SNPs.
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