Research Article
Transcriptome-Based Modeling Reveals that Oxidative Stress Induces Modulation of the AtfA-Dependent Signaling Networks in Aspergillus nidulans
Table 1
Gene enrichment analysis of AtfA-dependent genes.
| | Analyzed gene group | Significant shared GO and FunCat terms | Stress dependence |
| | AtfA-dependent upregulated genes | | | | | Alpha-amino acid biosynthetic process (GO) | tBOOH | | | Degradation of isoleucine, methionine, valine, arginine (FunCat) | tBOOH | | | Peroxisomal transport (FunCat) | tBOOH | | | Fatty acid metabolic process (GO) | tBOOH | | AtfA-dependent downregulated genes | | | | | Mitotic cell cycle (GO) | MSB, tBOOH, diamide | | | Mitotic sister chromatid segregation (GO) | MSB, tBOOH, diamide | | | Cytokinesis (GO) | MSB, tBOOH | | | Ribosome biogenesis (GO) | tBOOH | | | Translation (GO) | MSB, tBOOH | | | Tricarboxylic acid cycle (FunCat) | MSB | | | Aerobic respiration (FunCat) | tBOOH | | | Homeostasis of metal ions (Na, K, Ca, etc.) (FunCat) | diamide | | | ER to Golgi vesicle-mediated transport (GO) | MSB |
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The full lists of the significant shared biological process terms are available in Supplementary Table 3.
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