Research Article

Effect of Gegen Qinlian Decoction on Cardiac Gene Expression in Diabetic Mice

Table 2

Genes significantly regulated in the GGQL group versus the DB group and also significantly regulated in the DB group versus the WT group.

Gene nameDescriptionAdjusted value (DB/WT)Adjusted value (GGQL/DB)

Pgam1Phosphoglycerate mutase 1<0.00010.0038
Igf1Insulin-like growth factor 10.00600.0029
Cpeb4Cytoplasmic polyadenylation element binding protein 40.01410.0283
Slc38a2Solute carrier family 38, member 20.0000<0.0001
VegfaVascular endothelial growth factor A0.00010.0005
BanpBTG3-associated nuclear protein<0.00010.0100
Rbm38RNA-binding motif protein 380.00780.0380
Rasgef1bRasGEF domain family, member 1B0.00030.0037
Anxa3Annexin A3<0.00010.0309
Cyp1a1Cytochrome P450, family 1, subfamily a, polypeptide 1<0.00010.0016
Trib1Tribbles homolog 1 (Drosophila)0.00040.0118
Nphp3Nephronophthisis 3 (adolescent)<0.00010.0275
Fhl3Four and a half LIM domains 30.00360.0045
Serpine1Serine (or cysteine) peptidase inhibitor, clade E, member 1<0.00010.0016
Acer2Alkaline ceramidase 2<0.00010.0016
Arhgap32Rho GTPase activating protein 32<0.0001<0.0001
Atf4Activating transcription factor 40.00440.0016
Zc3h6Zinc finger CCCH type containing 6<0.00010.0136
Tet1Tet methylcytosine dioxygenase 10.00060.0016
Klk1b26Kallikrein 1-related petidase b260.01460.0189
Ppp1r3cProtein phosphatase 1, regulatory (inhibitor) subunit 3C0.00000.0029
Ttc30bTetratricopeptide repeat domain 30B<0.00010.0054
FignFidgetin<0.00010.0195
AI593442Expressed sequence AI593442<0.00010.0350
5730480H06RikRIKEN cDNA 5730480H06 gene0.00190.0029
Gm26703Predicted gene, 26703<0.0001<0.0001

Genes with an adjusted value < 0.05 were considered to be differentially expressed.