Research Article
Effect of Gegen Qinlian Decoction on Cardiac Gene Expression in Diabetic Mice
Table 3
Genes significantly regulated in the GGQL group versus the DB group but no differential expression in the DB group versus the WT group.
| Gene name | Description | Adjusted value (DB/WT) | Adjusted value (GGQL/DB) |
| Gatsl3 | GATS protein-like 3 | 0.4265 | <0.0001 | Abca8b | ATP-binding cassette, subfamily A (ABC1), member 8b | 1 | 0.0195 | Apex2 | Apurinic/apyrimidinic endonuclease 2 | 0.8103 | 0.0077 | Dnajb4 | DnaJ (Hsp40) homolog, subfamily B, member 4 | 0.1556 | 0.0071 | Vgll4 | Vestigial-like 4 (Drosophila) | 0.9649 | 0.0136 | Klhl36 | Kelch-like 36 | 0.1950 | 0.0136 | Amotl2 | Angiomotin-like 2 | 0.0637 | 0.0030 | Cish | Cytokine inducible SH2-containing protein | 0.4114 | <0.0001 | Myo6 | Myosin VI | 1 | 0.0483 | Caskin2 | CASK-interacting protein 2 | 0.8910 | 0.0158 | Baz1a | Bromodomain adjacent to zinc finger domain 1A | 0.2177 | 0.0020 | Fbxw17 | F-box and WD-40 domain protein 17 | 0.6014 | 0.0480 | Ddx60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.9151 | 0.0097 | Gck | Glucokinase | 0.1227 | 0.0112 | Zfp507 | Zinc finger protein 507 | 0.6355 | 0.0201 | Zfp518a | Zinc finger protein 518A | 1 | 0.0416 | Dusp7 | Dual specificity phosphatase 7 | 0.7537 | 0.0416 | Ifnlr1 | Interferon lambda receptor 1 | 0.3676 | 0.0275 | Rnasel | Ribonuclease L (2,5-oligoisoadenylate synthetase-dependent) | 1 | 0.0275 | Zfp763 | Zinc finger protein 763 | 0.2005 | 0.0063 | RP23-402K24.5 | RIKEN cDNA 6230415J03 gene | 0.4670 | 0.0350 |
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Genes with an adjusted value < 0.05 were considered to be differentially expressed.
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