Association of PTPN22 Haplotypes (−1123G>C/+1858C>T) with Rheumatoid Arthritis in Western Mexican Population
Table 1
Demographic and clinical characteristics of RA patients.
Variables
RA ()
CS ()
Demographic and clinic characteristics
Age
48 (18–82)
36 (18–74)
Sex%
Males
7 (23)
40 (127)
Females
93 (292)
60 (188)
29 (71)
9 (29)
Disease status
Duration of disease
10 (0.1–52)
—
—
Spanish HAQ-DI
0.76 (0–2.28)
—
Autoantibodies
Rheumatoid factor
178 (15–717)
15 (0–62)
Negative (<20
16 (50)
95 (300)
Low positive (20–59.9
21 (65)
5 (15)
High positive (≥60
63 (200)
0 (0)
Anti-CCP
119 (2–460)
1.5 (0.9–2.5)
Negative (<5
17 (52)
100 (315)
Low positive (5.1–14.9
9 (27)
0 (0)
High positive (≥15
74 (236)
0 (0)
presented in median (p25–p75). provided in percentage and n. provided in mean ± SD. RA: rheumatoid arthritis; CS: control subject; Anti-CCP: anticyclic citrullinated peptide antibody; DAS28: disease activity score 28; Spanish HAQ-DI: Spanish version of the Health Assessment Questionnaire Disability Index.