Relationship of SNP rs2645429 in Farnesyl-Diphosphate Farnesyltransferase 1 Gene Promoter with Susceptibility to Lung Cancer

Table 2

Genotypic and allelic frequency of FDFT1 polymorphisms in NSCLC patients and control group.

	Control; ()	NSCLC; ()	OR (95% CI)	value
Age (years)	62.32 ± 4.12	61.08 ± 7.93
Gender				0.46^a
Male	39 (64)	15 (44)	0.71 (0.28–1.77)
Female	22 (36)	12 (56)	Reference
Smoking status
Smoker	25 (65.9)	13 (34.1)	0.89 (0.38–2.11)	0.79^a
Nonsmoker	36 (63.2)	21 (36.8)	Reference
Codominant
CC, n (%)	37 (60.65)	28 (82.35)		0.09^a
CT, n (%)	19 (31.15)	5 (14.7)
TT, n (%)	5 (8.2)	1 (2.95)
Dominant
CC, n (%)	37 (60.65)	28 (82.35)	3.02 (1.09–8.39)	0.029^a
CT + TT, n (%)	24 (39.35)	6 (17.65)
Recessive
TT, n (%)	5 (8.2)	1 (2.95)	0.33 (0.03–3.03)	0.31^a
CT + CC, n (%)	56 (91.8)	33 (97. 05)
Allele
C, n (%)	93 (76.23)	61 (89.7)	2.71 (1.12–6.59)	0.023^a
T, n (%)	29 (23.77)	7 (10.3)	Reference

^aBased on chi-square test.