Research Article
Relationship of SNP rs2645429 in Farnesyl-Diphosphate Farnesyltransferase 1 Gene Promoter with Susceptibility to Lung Cancer
Table 2
Genotypic and allelic frequency of FDFT1 polymorphisms in NSCLC patients and control group.
| | Control () | NSCLC () | OR (95% CI) | value |
| Age (years) | 62.32 ± 4.12 | 61.08 ± 7.93 | | | Gender | | | | 0.46a | Male | 39 (64) | 15 (44) | 0.71 (0.28–1.77) | Female | 22 (36) | 12 (56) | Reference | Smoking status | | | | | Smoker | 25 (65.9) | 13 (34.1) | 0.89 (0.38–2.11) | 0.79a | Nonsmoker | 36 (63.2) | 21 (36.8) | Reference | Codominant | | | | | CC, n (%) | 37 (60.65) | 28 (82.35) | | 0.09a | CT, n (%) | 19 (31.15) | 5 (14.7) | | | TT, n (%) | 5 (8.2) | 1 (2.95) | | | Dominant | | | | | CC, n (%) | 37 (60.65) | 28 (82.35) | 3.02 (1.09–8.39) | 0.029a | CT + TT, n (%) | 24 (39.35) | 6 (17.65) | | | Recessive | | | | | TT, n (%) | 5 (8.2) | 1 (2.95) | 0.33 (0.03–3.03) | 0.31a | CT + CC, n (%) | 56 (91.8) | 33 (97. 05) | | | Allele | | | | | C, n (%) | 93 (76.23) | 61 (89.7) | 2.71 (1.12–6.59) | 0.023a | T, n (%) | 29 (23.77) | 7 (10.3) | Reference | |
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aBased on chi-square test.
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