Whole Exome Sequencing Uncovers Germline Variants of Cancer-Related Genes in Sporadic Pheochromocytoma

Figure 1

Deletion of the wild-type allele occurred in PCC samples that carry NF1 or VHL somatic mutations. Alignments of sequencing reads located on NF1 or VHL mutated bases are shown. Green bars represent deleted regions of chr3 for VHL (a, b) and chr17 for NF1 (c, d) detected by copy number analysis. A black arrow indicates the chromosome position of NF1 or VHL and the mutated base on the sequencing reads.

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