Research Article
Mutations in Homocysteine Metabolism Genes Increase Keratin N-Homocysteinylation and Damage in Mice
Table 1
Hcy- and S-Hcy-keratin levels and solubility in animal hair.
| | Animal () | Hcy-keratin (pmol/mg hair) | S-Hcy-keratin (pmol/mg hair) | Hcy-keratin/(Hcy-keratin + S-Hcy-keratin) | SDS-insoluble Hcy-keratin fraction |
| | Cat (5) | 278 ± 157 | 422 ± 214 | 0.60 ± 0.16 | 0.70 ± 0.05 | | Cow (5) | 556 ± 552 | 112 ± 54 | 0.70 ± 0.28 | 0.87 ± 0.11 | | Chipmunk (3) | 200 ± 193 | 395 ± 189 | 0.56 ± 0.04 | 0.73 ± 0.01 | | Dog (3) | 430 ± 80 | 386 ± 456 | 0.62 ± 0.29 | 0.69 ± 0.08 | | Goat (2) | 177 ± 127 | 217 ± 16 | 0.42 ± 17 | 0.80± 0.10 | | Guinea pig (1) | 56 | 253 | 0.18 | 0.67 | | Horse, tail hair base (10) | 189 ± 230 | 48 ± 40 | 0.30 ± 0.25 | 0.92 ± 0.05 | | Horse, tail hair tip 60 cm (10) | 1733 ± 882 | 31 ± 5 | 0.96 ± 0.01 | 1.00 ± 0.00 | | Mammoth (3) | 688 ± 72 | 49 ± 20 | 0.93 ± 0.03 | 0.67 ± 0.20 | | Opossum (2) | 484 ± 147 | | | | Pig (2) | 210 ± 206 | 131 ± 117 | 0.60 ± 0.04 | 0.67 ± 0.12 | | Rabbit (3) | 146 ± 75 | 265 ± 59 | 0.35 ± 0.16 | 0.76 ± 0.03 | | Raccoon (3) | 147 ± 58 | 212 ± 50 | 0.40 ± 0.04 | 0.66 ± 0.04 | | Sheep (3) | 310 ± 15 | 271 ± 36 | 0.53 ± 0.02 | 0.67 ± 0.19 | | Squirrel (3) | 352 ± 433 | | | | Woodchuck (3) | 733 ± 483 | 531 ± 474 | 0.57 ± 0.16 | 0.75 ± 0.09 | | Robin (4) | 203 ± 134 | 76 | 0.80 | 0.92 | | Raven (1) | 246 | 62 | 0.80 | 0.93 | | Turkey vulture (1) | 125 | 72 | 0.63 | 0.81 | | Pigeon (1) | 716 | 87 | 0.89 | 0.91 | | Seagull (1) | 493 | 114 | 0.81 | 0.78 |
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