Ensemble Methods with Voting Protocols Exhibit Superior Performance for Predicting Cancer Clinical Endpoints and Providing More Complete Coverage of Disease-Related Genes

Table 7

Coverage of the selected genes from mRNA.

Disease	ShareNum	Subdata scale
		10	30	50	100
BRCA	5	0	2	2	5
	4	4	5	10	25
	3	4	13	21	45
	2	2	16	26	42
	1	18	49	85	156
	Total	28	85	144	273
	Coverage fraction	35.7%	42.4%	40.1%	42.9%
KIRC	5	0	0	0	2
	4	0	3	3	8
	3	2	6	14	28
	2	6	22	34	71
	1	32	76	128	232
	Total	40	107	179	341
	Coverage fraction	20%	29%	28.5%	32%
OV	5	0	1	2	5
	4	1	2	7	16
	3	1	8	16	55
	2	9	27	34	43
	1	25	59	96	160
	Total	36	97	155	279
	Coverage fraction	30.6%	39.2%	38.1%	42.7%

The coverage fraction is the number of the genes which are used more than once in all of the genes, and accordingly, the formula is . The ShareNum is the number of a gene used in the subdatasets. For example, in Table 7, the value in the OV-miRNA group with ShareNum 3 and data scale 10 is 1; it means that there is one gene which is used by 3 subdatasets and each subdataset has 10 microRNAs as the attributes.