Metabolic Pathway Genes Associated with Susceptibility Genes to Coronary Artery Disease

Table 2

The canonical variable delegate integrates metabolic pathways.

Metabolic pathways	Gene number	r	Sa	Sb	Represent gene ID
Citrate cycle (TCA cycle)	30	0.90	0.20	0.19	, , , , ,
Ubiquinone and other terpenoid quinone biosyntheses	10	0.90	0.30	0.93	27235, 84274, 79001
N-glycan biosynthesis	48	0.96	0.23	0.28	4247, 4248, 85365, 1650, 11282, 79868, 57134, 8813, 4122, 146664, 29929
Other glycan degradation	17	0.92	0.27	0.62	10825, 2720, 3074, 129807, 2519
Glycosaminoglycan degradation	17	0.91	0.22	0.69	2720, 3074, 6677, 2799
Glycosylphosphatidylinositol (GPI) anchor biosynthesis	25	0.93	0.21	0.43	9091, 284098, 2822, 5281, 5279
Glycosphingolipid biosynthesis–ganglioseries	15	0.93	0.22	0.92	2583, 2720, 3074

S_a and S_b indicate the extent of canonical variables covering the whole pathway. The representative genes were selected based on the percentage of covering (gene number in pathways S_b).