Multitarget Effects of Danqi Pill on Global Gene Expression Changes in Myocardial Ischemia
Table 3
Top ten significantly enriched GO biological processes among upregulated and downregulated genes in ischemic heart. The GO terms are ranked according to the order of the increasing values. Gene count referred to the number of genes among all the GO member genes.
Gene ontology ID and terms
Gene count
value
Upregulated
GO:0009611~response to wounding
39
4.65E − 16
GO:0030198~extracellular matrix organization
16
6.64E − 11
GO:0001501~skeletal system development
24
7.24E − 10
GO:0060348~bone development
17
1.11E − 09
GO:0032535~regulation of cellular component size
22
1.92E − 09
GO:0001503~ossification
16
2.21E − 09
GO:0001558~regulation of cell growth
19
2.34E − 09
GO:0040008~regulation of growth
24
7.57E − 09
GO:0043062~extracellular structure organization
16
4.00E − 08
GO:0008361~regulation of cell size
18
6.08E − 08
Downregulated
GO:0006091~generation of precursor metabolites and energy
12
1.60E − 05
GO:0044275~cellular carbohydrate catabolic process
