Table 3: Top ten significantly enriched GO biological processes among upregulated and downregulated genes in ischemic heart. The GO terms are ranked according to the order of the increasing values. Gene count referred to the number of genes among all the GO member genes.

Gene ontology ID and termsGene count value

UpregulatedGO:0009611~response to wounding394.65E − 16
GO:0030198~extracellular matrix organization166.64E − 11
GO:0001501~skeletal system development247.24E − 10
GO:0060348~bone development171.11E − 09
GO:0032535~regulation of cellular component size221.92E − 09
GO:0001503~ossification162.21E − 09
GO:0001558~regulation of cell growth192.34E − 09
GO:0040008~regulation of growth247.57E − 09
GO:0043062~extracellular structure organization164.00E − 08
GO:0008361~regulation of cell size186.08E − 08

DownregulatedGO:0006091~generation of precursor metabolites and energy121.60E − 05
GO:0044275~cellular carbohydrate catabolic process76.08E − 05
GO:0006007~glucose catabolic process62.01E − 04
GO:0055114~oxidation reduction172.14E − 04
GO:0046365~monosaccharide catabolic process62.37E − 04
GO:0019320~hexose catabolic process62.37E − 04
GO:0046395~carboxylic acid catabolic process73.17E − 04
GO:0016054~organic acid catabolic process73.17E − 04
GO:0016052~carbohydrate catabolic process73.36E − 04
GO:0043648~dicarboxylic acid metabolic process54.94E − 04