Table 4: Enriched downregulated pathways and biological processes by DQP treatment.

Term% valueGenes

KEGG pathway
Staphylococcus aureus infection3.60.000015C1QA, C1QB, C5AR1, LOC498276, CFH, RT1-DMA, C1QC
Phagosome4.10.003ACTB, RAB5C, NCF4, LOC498276, SCARB1, RT1-DMA, TUBA1C, SEC61A1
Complement and coagulation cascades2.60.006C1QA, C1QB, C5AR1, CFH, C1QC
African trypanosomiasis2.10.006VCAM1, F2RL1, LOC100134871, HBB
Leukocyte transendothelial migration3.10.007ACTB, VCAM1, MYL7, NCF4, CLDN5, MMP2
Tuberculosis3.60.010LSP1, RAB5C, LOC498276, TGFB3, FCER1G, RT1-DMA, LBP
Platelet activation3.10.011ACTB, GP1BB, LOC498276, COL3A1, FCER1G, COL5A2
ECM-receptor interaction2.60.012GP1BB, COL3A1, COL5A2, SPP1, FN1
Glutathione metabolism2.10.020GSTA3, GPX3, GSTT1, GPX7
Malaria2.10.021VCAM1, LOC100134871, TGFB3, HBB

GO_biological process
Cell adhesion6.70.000017IGFBP7, COL16A1, VCAM1, WISP2, CTGF, GP1BB, FBLN5, VCAN, GPNMB, SPON1, FN1, AOC3, SPP1
Regulation of cell growth3.60.000045WISP2, CREB3, CTGF, IGFBP7, FBLN5, IGFBP6, IGFBP4
Aging6.20.00042VCAM1, C1QB, GSTA3, LITAF, CTGF, ELN, COL3A1, TGFB3, TIMP2, TIMP3, MMP2, AOC3
Collagen fibril organization2.60.001COL3A1, LOXL2, COL5A2, ANXA2, DPT
Positive regulation of fibroblast proliferation3.10.001FBLN1, TGIF1, AQP1, MYC, ANXA2, FN1
Integrin-mediated signaling pathway3.10.002FBLN1, CTGF, ADAMTS15, COL3A1, FCER1G, TYROBP
Elastic fiber assembly1.50.003FBLN5, ELN, MFAP4
Neutrophil chemotaxis2.60.003C5AR1, LGALS3, FCER1G, CCL19, SPP1
Extracellular matrix organization3.10.003FBLN1, LGALS3, FBLN5, ELN, CCDC80, FN1
Ossification3.10.003ALOX15, CTGF, MGP, COL5A2, SPP1, FN1