Additional Evidence for DDB2 T338M as a Genetic Risk Factor for Ocular Squamous Cell Carcinoma in Horses

Figure 2

Association testing of variants identified from analysis of resequencing data in Haflingers phenotyped for ocular SCC. The DDB2 variant (c.1013 C>T) was the most concordant with ocular SCC phenotype in a population of 118 Haflingers (56 cases and 62 controls). Other variants that were strongly associated but less concordant with ocular SCC phenotype include 12:g.11239116A>G (CKAP5), 12:g.11655415T>C (MADD), 12:g.12004291C>T (FNBP4). -log₁₀ values for each polymorphism are presented for the sample set.