Identification and Validation of Core Genes Involved in the Development of Papillary Thyroid Carcinoma via Bioinformatics Analysis

Table 4

Top 10 genes with high node degrees in PPI network.

Node	Degree	GSE33630		GSE35570		GSE60542
		Log2FC	Adj.	Log2FC	Adj.	Log2FC	Adj.
TGFB1	73	1.62		2.52		1.46
JUN	67	-1.38		-1.55		-1.69
CXCL8	62	2.01		1.88		1.11
LRRK2	59	4.26		5.98		3.59
CD44	56	1.88		1.54		1.38
DCN	47	-1.88		-2.26		-1.75
BCL2	46	-1.72		-1.78		-1.88
ACACB	42	-1.11		-1.56		-1.45
CCND1	42	1.71		1.51		1.27
CXCL12	40	-1.56		-1.76		-1.74

Notes: The adj. value was calculated using Student’s -test. Abbreviations: PPI, protein-protein interaction.