Genus-Wide Comparative Genomics Analysis of Neisseria to Identify New Genes Associated with Pathogenicity and Niche Adaptation of Neisseria Pathogens

Table 1

Genomic details of Neisseria species used in the present study.

Organism	Accession number	Genome size (bp)	GC content (%)	# of scaffolds	# of plasmids	# of ORFs	rRNA	tRNA	Morphology	Natural host	Reference
Neisseria gonorrhoeae									Diplococcus	Human
32867	CP016015	2,218,818	52.41	1	0	2545	12	55
34530	CP016016	2,228,373	52.35	1	0	2557	12	55
34769	CP016017	2,220,340	52.43	1	0	2541	12	55
35_02	CP012028	2,173,235	52.6	1	0	2468	12	55			[57]
FA_1090	AE004969	2,153,922	52.69	1	0	2448	12	55
FA19	CP012026	2,232,367	52.38	1	0	2573	12	55			[57]
FA6140	CP012027	2,168,698	52.59	1	0	2485	12	55			[57]
FDAARGOS_204	CP020415	2,212,422	52.45	1	0	2541	12	55
FDAARGOS_205	CP020417	2,278,895	52.26	1	2	2665	12	54
FDAARGOS_207	CP020419	2,189,343	52.36	1	0	2497	12	55
MS11	CP003909	2,237,793	52.36	1	1	2591	12	55
NCCP11945	CP001051	2,236,178	52.36	1	1	2574	12	55			[58]
NCTC13798	NZ_LT906440	2,230,241	52.35	1	0	2551	12	55
NCTC13799	NZ_LT906437	2,172,222	52.56	1	0	2469	12	55
NCTC13800	NZ_LT906472	2,226,638	52.36	1	0	2549	12	55
Neisseria meningitidis									Diplococcus	Human, chimpanzee
53442	CP000381	2,153,416	51.7	1	0	2298	12	59			[59]
331401	CP012694	2,191,116	51.86	1	0	2361	12	59
38277	CP015886	2,264,278	51.4	1	0	2458	12	60
510612	CP007524	2,188,020	51.83	1	0	2368	12	59			[60]
8013	FM999788	2,277,550	51.43	1	0	2415	12	59			[61]
alpha14	AM889136	2,145,295	51.95	1	0	2279	12	58			[62]
alpha710	CP001561	2,242,947	51.69	1	0	2406	12	57			[63]
B6116_77	CP007667	2,187,672	51.66	1	0	2386	12	59			[64]
COL-201504-11	CP017257	2195,573	51.65	1	0	2372	12	59
DE10444	CP012392	2,170,619	51.63	1	0	2279	12	59
DE8555	CP012393	2,207,932	51.81	1	0	2394	12	59
DE8669	CP012391	2,230,103	51.42	1	0	2362	12	59
FAM18	AM421808	2,194,961	51.62	1	0	2324	12	59			[65]
FDAARGOS_209	CP020420	2,181,227	51.89	1	0	2364	12	59
FDAARGOS_210	CP020421	2,273,677	51.52	1	0	2414	12	59
FDAARGOS_211	CP020422	2,305,790	51.43	1	0	2469	12	59
FDAARGOS_212	CP020423	2,244,857	51.5	1	0	2426	12	59
FDAARGOS_214	CP020401	2,397,439	51.05	1	0	2621	12	59
FDAARGOS_215	CP020402	2,305,808	51.43	1	0	2473	12	59
G2136	CP002419	2,184,862	51.68	1	0	2352	12	59			[66]
H44_76	CP002420	2,240,883	51.45	1	0	2379	12	59			[66]
L91543	CP016684	2,173,191	51.72	1	0	2357	12	59
LNP21362	CP006869	2,139,957	51.82	1	0	2297	12	59
M01-240149	CP002421	2,223,518	51.44	1	0	2360	12	59			[66]
M01-240355	CP002422	2,287,777	51.5	1	0	2413	12	59			[66]
M04-240196	CP002423	2,250,449	51.4	1	0	2383	12	59			[66]
M0579	CP007668	2324,822	51.37	1	0	2456	12	59
M07149	CP016650	2,173,513	51.73	1	0	2377	12	59
M07161	CP016675	2,169,790	51.75	1	0	2385	12	59
M07162	CP016644	2,193,742	51.67	1	0	2413	12	59
M07165	CP016880	2,207,174	51.58	1	0	2442	12	59
M07999	CP016881	2,162,082	51.77	1	0	2361	12	59
M08000	CP016681	2,162,376	51.77	1	0	2357	12	59
M08001	CP016652	2,162,199	51.78	1	0	2359	12	59
M09261	CP016665	2,154,341	51.82	1	0	2351	12	59
M09293	CP016648	2,161,510	51.78	1	0	2366	12	59
M10208	CP009422	2,183,230	51.68	1	0	2434	12	59
M12752	CP016645	2,173,879	51.73	1	0	2370	12	59
M22160	CP016674	2,177,343	51.73	1	0	2381	12	59
M22189	CP016649	2,172,699	51.74	1	0	2372	12	59
M22191	CP016683	2,155,494	51.82	1	0	2337	12	59
M22718	CP016627	2,173,408	51.73	1	0	2367	12	59
M22722	CP016663	2,172,888	51.73	1	0	2370	12	59
M22740	CP016679	2,172,899	51.73	1	0	2366	12	59
M22745	CP016657	2,163,399	51.77	1	0	2357	12	59
M22747	CP016882	2,173,015	51.73	1	0	2375	12	59
M22748	CP016653	2,157,503	51.78	1	0	2359	12	59
M22759	CP016669	2,168,308	51.74	1	0	2342	12	59
M22769	CP016656	2,168,495	51.74	1	0	2344	12	59
M22772	CP016655	2,173,607	51.73	1	0	2366	12	59
M22783	CP016671	2,180,570	51.64	1	0	2334	12	59
M22790	CP016883	2,168,169	51.67	1	0	2360	12	59
M22797	CP016884	2,193,498	51.76	1	0	2406	12	59
M22801	CP016659	2,172,426	51.73	1	0	2376	12	59
M22804	CP016660	2,174,791	51.65	1	0	2325	12	59
M22809	CP016647	2,182,171	51.63	1	0	2332	12	59
M22811	CP016654	2,185,698	51.62	1	0	2342	12	59
M22819	CP016646	2,173,686	51.65	1	0	2308	12	59
M22822	CP016680	2,173,901	51.67	1	0	2334	12	59
M22828	CP016672	2,172,926	51.67	1	0	2318	12	59
M23413	CP016662	2,173,723	51.73	1	0	2372	12	59
M24705	CP016682	2,175,832	51.66	1	0	2327	12	59
M24730	CP016658	2,175,362	51.74	1	0	2369	12	59
M25070	CP016664	2,168,001	51.73	1	0	2372	12	59
M25073	CP016885	2,204,403	51.59	1	0	2415	12	59
M25074	CP016886	2,211,323	51.56	1	0	2440	12	59
M25087	CP016670	2,167,991	51.72	1	0	2365	12	59
M25419	CP016678	2,189,560	51.71	1	0	2373	12	59
M25438	CP016661	2,171,975	51.74	1	0	2369	12	59
M25456	CP016677	2,173,106	51.73	1	0	2371	12	59
M25459	CP016673	2,173,115	51.73	1	0	2376	12	59
M25462	CP016666	2,174,042	51.73	1	0	2378	12	59
M25472	CP016668	2,170,146	51.72	1	0	2370	12	59
M25474	CP016651	2,172,576	51.73	1	0	2364	12	59
M25476	CP016676	2,168,191	51.73	1	0	2370	12	59
M27559	CP016667	2,173,745	51.73	1	0	2369	12	59
M7124	CP009419	2,179,483	51.73	1	0	2372	15	61
MC58	AE002098	2,272,360	51.53	1	0	2412	12	59			[67]
NM3682	CP009420	2,196,674	51.64	1	0	2388	13	59
NM3683	CP009421	2,199,215	51.64	1	0	2384	14	61
NM3686	CP009418	2195,266	51.65	1	0	2365	12	59
NZ-05_33	CP002424	2,248,966	51.33	1	0	2385	12	59			[66]
WUE2121	CP012394	2,206,847	51.82	1	0	2403	12	59
WUE_2594	FR774048	2,227,255	51.84	1	0	2425	12	55			[68]
Z2491	AL157959	2,184,406	51.81	1	0	2335	12	58			[69]
Nonpathogenic Neisseria species
N. lactamica 020-06	FN995097	2,220,606	52.28	1	0	2372	12	59	Diplococcus	Human	[70]
N. lactamica ATCC 23970	KN046803	2,182,033	52.17	1	0	2294	12	57	Diplococcus	Human
N. lactamica Y92-1009	CP019894	2,146,723	52.34	1	0	2298	12	58	Diplococcus	Human
N. mucosa C102	GL635799	2,169,437	49.42	7	0	2132	3	54	Diplococcus	Human, dog, duck, dolphin
N. weaveri NCTC13585	LT571436	2,188,497	49	1	0	2195	12	55	Bacillus	Human, dog
N. zoodegmatis NCTC12230	NZ LT906434	2,552,522	50.94	1	0	2668	12	55	Coccobacillus	Human, dog
N. elongata ATCC 29315	CP007726	2,256,647	54.26	1	0	2464	12	61	Coccobacillus	Human	[71]

Note. Latin name, accession number, genome size, GC content, number of scaffolds, number of plasmids, number of ORFs, rRNA, tRNA, morphology, natural host, and reference are listed.