Research Article

Integrated Bioinformatic Analysis Identifies Networks and Promising Biomarkers for Hepatitis B Virus-Related Hepatocellular Carcinoma

Figure 2

Volcano plots and Venn diagrams of differentially expressed genes (DEGs) selected from three Gene Expression Omnibus (GEO) datasets. (a) Volcano plots of DEGs in normal and tumoral liver samples of HCC patients with HBV infection in GSE47197, GSE55092, and GSE121248. DEGs were filtered by adjusted value < 0.05 and . The red and green dots display the distribution of all the significant upregulated (red dots) and downregulated (green dots) DEGs in the three datasets, respectively. (b, c) The Venn diagrams of overlapping DEGs from an intersection of upregulated and downregulated genes in the three datasets.