Integrated Bioinformatic Analysis Identifies Networks and Promising Biomarkers for Hepatitis B Virus-Related Hepatocellular Carcinoma

Table 1

329 differentially expressed genes (DEGs) (67 upregulated and 262 downregulated) filtered by the integration of three microarray datasets.

DEGs	Gene name
Upregulated	SPINK1 TKT HSPB1 TPX2 S100P CCNB1 CLGN ASPM FLVCR1 CCDC34 AKR1B10 GINS1 KNL1 KPNA2 SMYD3 BIRC5 STIL UBE2C THBS4 FOXM1 EZH2 CCNB2 PRC1 CDK1 FABP5 CENPW RACGAP1 FANCI CENPU AURKA MCM3 DTL FAM83D TOMM40L HMMR THY1 GPC3 CDKN2C CCL20 SPP1 KIF2C SQLE LCN2 AKR1C3 SFN PEG10 UHRF1 HN1 ZWINT CDKN2A NDC80 KIAA0101 REG3A RFC4 OIP5 CDKN3 PBK TRIP13 PTTG1 STMN1 UBE2T CRNDE CENPF NUSAP1 CD109 TP53I3 DEPDC1
Downregulated	CYP26A1 BBOX1 XDH CXCL14 ACOT12 IGF1 HSD17B2 CYP39A1 EPB41L4A C1R PROZ C8A HRG ZG16 DEPDC7 MBL2 RCL1 SLCO1B3 SORL1 TRPM8 BCO2 DEFB1 TEK DACH1 TMEM45A FAM150B FOLH1B GHR CLEC1B CCL19 BHMT PON1 POU2AF1 STEAP3 SHBG ATOH8 DNASE1L3 BCHE HAO1 ID1 GPD1 FAM110C CRHBP ASS1 F9 IDO2 IGFALS SLC38A4 ACADL DBH TBXA2R CRP COLEC11 SLC39A5 SRD5A2 EGR1 ECM1 AKR7A3 SLC3A1 MS4A6A FCN2 CYP4V2 KLKB1 F11 MT1G ABCA8 SLC19A3 PGLYRP2 LINC01093 STEAP4 SLC22A1 ALDH6A1 ZFP36 MFSD2A ANO1 APOA5 HOGA1 CHST4 CFHR4 PPP1R3B RCAN1 MAN1C1 PANK1 PHGDH ARG1 PCK1 KBTBD11 SULT2A1 ADH1C DPYS CYP2C9 CYP2A7 CYP2E1 SULF2 CTH CLEC4M GABARAPL1 ESR1 ADAMTSL2 RND3 IL1RAP RDH16 ANG DMGDH TMEM27 AFM HPGD MFAP3L THRSP CYP4A11 AGXT2 NR4A3 MT1X SERPINF2 S100A8 C7 MRC1 TBX15 BMPER AADAT CCL2 NNMT SERPINA4 EPHX2 APOF GCDH FAM13A GADD45B GRAMD1C SLC7A2 TUBE1 GREM2 SDS ETNPPL DPT PRKAR2B LUM HPD SLC25A47 FLJ22763 SKAP1 EXOC3L4 SLC10A1 NAMPT ACADSB MT1E ANXA10 TTC36 GYS2 SH3YL1 ETFDH CD5L LPA C8B CXCL2 SLC22A7 TAT LIFR CYP4F2 PLGLB2 COLEC10 VNN1 LYVE1 CYP2C18 FGA FOS ALDH8A1 NAT2 MASP2 AKR1D1 PAMR1 CXCL12 GNMT TACSTD2 A1BG ACSL1 SLC16A4 CA2 FBP1 ADH4 OIT3 GLYAT ADH1A ANGPTL6 CFTR CETP INMT HBB SRPX ENO3 LECT2 ADAMTS13 PLG SOCS2 SLC13A5 CCL5 SPP2 HAO2 ACMSD IL33 HHIP ADH1B KCNN2 GSTZ1 LY6E CPS1 CNDP1 TKFC FCN3 ACACB GBA3 PDGFRA RNF125 CLEC4G OTC CDH19 FXYD1 HPX KMO ANK3 FOSB FAM65C SLC27A2 MARCO ADH6 LCAT MT1H TDO2 VIPR1 IGFBP3 PLAC8 GPT2 CFP CYP8B1 CD69 FTCD CIDEB TFPI2 LHX2 STAB2 HGFAC PTH1R MT2A NRG1 ADGRG7 CDA ZGPAT OGDHL PZP CYR61 CP HSD17B6 SLC27A5 JCHAIN GLS2 SLC51A C6 PTGIS C9 FBLN5 CDHR2 OAT